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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7880e002bb9906fcef86eb7f7077332d188164f047fdb63ed957c61730c7b9f' 
  AND token = 'GRw3zrZU+FFN3kXa69lA1TRXRa55FZ7VeGjr2h7ELEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}