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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d4d1d8e236088df268e9a37ee856eb5725e5ef976e61c6044a6ff8e911d6eb' 
  AND token = 'VjDIOvhmfsxPCC2qGdEOBTCv1ofYIuO6OEFBir3FkHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}