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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9b57296769c4dfce22042131217e73b277fb0f6ef6b49572e6a192d8da1af38' 
  AND token = 'nHUB17rU9A0/6HirqvnD2S0nozjPd6zW4SOhqpvFTak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}