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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d1671edc4ca6abda498df35fe5643d836fb28b3a0806c24ac18fec3fd4c80a0' 
  AND token = 'zm5Q3k0F25pq2zzlEEY3te1TA5zUYqWjbR8wLHmrK2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}