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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20df0e3f0f4fe93493051d4b6aa00b04adc700623fac0d61ecdd7d5fef505c7c' 
  AND token = 'jOaTWrVL2z/YsSq+T5+YbHd6G9xYPtZ97CtlUkXJRR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}