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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf9b1d008dabcee527216a2a5b13366101bc41fbb7ed5b60b6074e3a34d04ba3' 
  AND token = 'efWYgvcvj4sdFf0BH0LMsBCXIeqyH1LQkzzL3bLJ3Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}