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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da27a373b018bb600c78df9b4b7034d30da6adf1cefe01a1c3e9a63f9971835a' 
  AND token = 'IA3ITByXPbKwfsYfxMAW44xVdA7JZvFgYC+k720slC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}