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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e33b96b6cdb3f30813bfb5048dd48b2fdc5f4275046c43e7e02db2406439802' 
  AND token = '+r/2/V5MmpQ4EcnhrfUIN/YaSerxio9PLYVp7XNJq8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}