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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b53df4f3b110d701f2d20868080bed1fda957a18a4f3e33a4a3474955bcb6c7' 
  AND token = 'zjo//d2x17KkMVJj1dRtR9Th4cQsrb+qmI76Dtc+/Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}