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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72227e54ff69114922aeaf14c5119623c898b225ab805b9f05e219e831b6bf63' 
  AND token = 'h5SYhP396ltaERhr7fKEqHi5SgI22svfvAluNrggqNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}