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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e643d72f789fa21da3f4fb7707de4738f8adc337b21925e6491a70fd9d4c49ed' 
  AND token = '0mw+yhan5NCmtG7yR35VqvDvBzebqtePbQIwP5SmHIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}