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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288eb6734817cca3e1f3e0b3a1640cdd184134b2afd19f5c85c1514f13c80fbb' 
  AND token = 'ZGgGr3ID1TwWpQJuFQf4LVgjHnX/0wbLjTH4hIeSoug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}