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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46347d8dd04295641b5d19808bab393f3cc00857ff2ae48f115444a648bef186' 
  AND token = '7jX2KOY0MehEjpimYPePC079jyaZYtId1vP8dox+d7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}