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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de43e5df4ca58b09233cebe631125d5669319e67657b8ff36c7f3ec72c25d7ca' 
  AND token = '4lLMNS0ELaYI3pKGD76NMAw9mu511l2yh9E0wNqA2+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}