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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac01af33da689023ef48fc794573e6a6d7c5fcedb7ba5a2997024720ad849ac1' 
  AND token = 'Uy5d9d2Y6EDbnBGe6DQB8R+blMcxaIIbG4oEE0EZxko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}