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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b35af3866f5dde8a9405bc01a00519b5dfe7469799c6493dec2f89bbf08a9a8' 
  AND token = 'nVTKDr80uu8S5fMLPmR6ebtzND9coE+sAmnkejS9HbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}