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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64470bf4a16a518306555afb484c6a0ea806e408178cf48d23c539d9477d1f00' 
  AND token = 'Pl3EP/w51eB5CF95+l39IyDrnpaSpqDnh9DQNkPYhM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}