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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff12ef8d43b69d44e4e1c6790ea4252f861925b813cebb01acfb5a4583dd900' 
  AND token = 'xJ+zM1HUAVlqgAS0ZYUQe8m1oJkiTgCi70SGcZGiaJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}