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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857faa237efde1b2b55269c958cb2a2a6cab970188106780f2652e74e0905b24' 
  AND token = '8cpQPFB+5C07qbFPOiTB+a/GzupQUrAfWVmc+eXkyiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}