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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c247aa254abd17a4e84b2a0aede1d6bfe0c7685fc29db7215d4f329b8e4e852' 
  AND token = 'uiNTDFySNYeP8Vt1GWhQ0AANWlXWe9Pm1/RSShxkyYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}