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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a552dd5dfca0061e6b3a8a1f9481b5b5f186153df4f4529402c1e6ecdc5ba3d0' 
  AND token = '/qBBr9pML2qzvZv5uvKLtoCQbrVQ07NkSCRTr1K7Biw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}