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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522bd79efb8684ae61d87015785d903f5952f49d008a17264df7c0b1d25ae177' 
  AND token = 'x+bjbkvW8p14HJqixmoPqg38oiAVUM5AEq3UMTZsrcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}