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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9069a4b1a2156805766c517f2df1b95a4c1288251a704336a57560572a4dac24' 
  AND token = 'vPbVkpHuPrtt2TAXDeWRhCjZ2bpRc0ptP0Anpic6sYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}