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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f51128468d8fa99a8565524366798768a4ab184480542d81420631d24db07f8b' 
  AND token = 'cGA+oj4Wsm8R2AjmtW/oKeMVCoAopxw2DZMn7Vpvi20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}