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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfc2073941a8903f2725e78ba98360cb0988399a8e1e21f1648bd368e73037bc' 
  AND token = '6rQwOK5+7xYIRQt6GX7yEEbfZL6Eq+sSU03HCRkU7Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}