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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd136f042ea4aeba8ac57925c06334e83540c43eee28e1517bfc721e24d4b41' 
  AND token = 'dhhWQHn4vkG2IPtXZoT1zjSMPRmVi+t5jFBmbciWVeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}