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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5b644a28bf6e5664fa14b01d2dc2fcbc0da83c3e769e8cd11c6241a7cb7aca' 
  AND token = 'P300QBm2D8zT/wz5vNR96Qix8AWdVbE9pp2OfmCo3Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}