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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'affee8161252e39a6fd12b546efd13707c09b232bfd5ac60210d2edf0e6d6ccf' 
  AND token = 'nmmuCqGwjGc0mOqg4Qbhl3g7mW+zgE1pnMB/xr2CCUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}