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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d3fabcbd349dfa600ee12892317775bda0d333a64ea2e19001f2a5c74da1d4' 
  AND token = 'DLl2bd+f8Hh/+gzJOIdtOUa3A1XaZh5byBhuHcQmpYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}