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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02a3671e341331107b997eb4f8c37e709e7c9a9bf24812c6130071a1bf395866' 
  AND token = 'tPfiGTFqD6myF7p/CTljeYxpsidfdHmfJrxVCNeRKFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}