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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c1fbecc866b860e56ae191c67a6f94b23e325f1440c05deab6af682b841f44' 
  AND token = 'Pr1nnlwrC4yYdsXMOZJX4HG2rsa9ZDYW4hQe9Uec0pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}