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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779f3b243505e39885b9e88645213b50018d30512742e1fbc65d80666ffc2dc1' 
  AND token = 'zpOzwyBLBdBbzcQ8dS5FPxeH0AoObk4rB+s9eCn4X+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}