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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99603d9f14de63e314e2e939b5b0903c9ec508deff385ebb6913428039e64da0' 
  AND token = 'ZxHCq3UgVUdgv6ivk+yY/HSPcBXR9foQmyWYB6XgC+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}