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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64da5f3445835a27f0fe6244535e93f5cd67a2f76d5f73d53470573b8bd64632' 
  AND token = 'muto3Zav9wgBBbLD7kA/zryavstMZN9lMmWsd6kArAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}