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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51cb89da08c5e04df0b916cc97457886d04c4273899ae6e813e97f86895ec154' 
  AND token = 'amJumi6ApG+emXTqxegMyZwQ+hYICrEEOESUzUDbzd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}