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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580ec2c136eb180498a50a3bf8ca52ff7a7b71d796fb30bac573e15af0b68144' 
  AND token = 'BAXwofTPcQQPlr5uhJFEF8AvtMwy6kME4TxFqtmkYos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}