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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aa94370b505dbe5805ce55caf87d2fbdbc81356b7277b86b93e5779febcbd5a' 
  AND token = 'jeVrfEM4InpZDDg9zBb8zoZVW4tG2GMHvlzS7cLVHvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}