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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80ec8cbdf1a0612866ab0c06131b7157d27171aa0b273d5a68078b373614ca7' 
  AND token = 'XcfPjr/nmbutIG9TQ0NbMTaSqt3yMOMr/Y2pASZDSoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}