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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25e684fc099f09042b0922b8e5bef0b34942a8399bf72d809ab0679ced4afb2' 
  AND token = '+XSkg4bmIbNEDjyFv1iYpZAewHWeEll2HY+RYBugJSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}