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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b644bc9fdf97738c033fe6784ffc3eeff1ddd6bbc31105fb3f1ea733660d12' 
  AND token = 'w+6PB4Co78MiJnifK67igu7vvTYL65zyuX296vlIOV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}