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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41ff04d21272e2c5bd73d623d70091c80aaf47c270f37bf355b5d10596355e3' 
  AND token = 'L1t1Jf9Fv4BCABJQ+9d7vSQrc0YY7By3zNRMIXwTIuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}