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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d15124ee299329426d3b7c4e3e1c603053ecc3ad1ab944865b724362506f90e' 
  AND token = 'qbdew33w0/eBQ4lGVi33t6YOEj+9hAz5E3gOeNvewO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}