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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '104a9712ec313f6732f6f7fcd65577d9f12cc7f246498c5f86ab936bf95e324a' 
  AND token = 'kvmr3zQ3nz1yJn+LglkQtAy/tbbL+csSR2U1RpdOmKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}