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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9e87e1bc63de2b2b54f3d4846ba59bcd5bf082d77a0a3109d64d8a172f45b81' 
  AND token = 'KEhhCbnoF/z95SwfefeWUevmBdEMXBcXx98DNWJijs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}