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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291df1c455f857e836eab13a149c98c4bd80fced0eea2cef66119100edc65f57' 
  AND token = '0JDR48X0bDcpa6hEjDfIdH9oXrqwFABnXjU58NgGvFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}