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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f51ab8d5fec0356a286344dbe37c0fdf7e7d69fdce19d8edabbd26a4c4226d61' 
  AND token = '1JMPMt0pNKl8TDjlMl6T5zhL5/2vqY9MshU06V1v4oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}