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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b66bdd6bcf892b3c4ecf21b5ca6c589a7264a5eb62155073e90f22ec56669e' 
  AND token = 'IbMQqtJ82QMs+YJwayBj6zL2kQAJIADISgESiNsvOJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}