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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01163527205644377a09c1a7f23a1b62e678c95ae2fff399b66d1d947b43402' 
  AND token = 'QI2S3dk2VTR/rMv0XgM8eYvkatx/ctwABgl202yy2tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}