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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '370b65b3d494b7eb4efb63caa0d2c0adfa29e8166bf64db26f07d50f1765291c' 
  AND token = '4QXHsQL2+ZrlQR4hx75smssheVqm/cRbf4dTVrKNK0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}