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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18fdd394533e6fdee5616bcdb23a7e090d32866ff3a2b7809a34ba50a3a6757c' 
  AND token = 'x/2jXJ+XsZsTf+JTTc249DinldepHe95Kg+Zh3B5POU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}